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BRN2 is a non-canonical melanoma tumor-suppressor.
Hamm M, Sohier P, Petit V, Raymond JH, Delmas V, Le Coz M, Gesbert F, Kenny C, Aktary Z, Pouteaux M, Rambow F, Sarasin A, Charoenchon N, Bellacosa A, Sanchez-Del-Campo L, Mosteo L, Lauss M, Meijer D, Steingrimsson E, Jönsson GB, Cornell RA, Davidson I, Goding CR, Larue L. Hamm M, et al. Among authors: le coz m. Nat Commun. 2021 Jun 17;12(1):3707. doi: 10.1038/s41467-021-23973-5. Nat Commun. 2021. PMID: 34140478 Free PMC article.
Quiescent melanocytes form primary cilia.
Le Coz M, Benmerah A, Larue L. Le Coz M, et al. Exp Dermatol. 2014 Jun;23(6):426-7. doi: 10.1111/exd.12426. Exp Dermatol. 2014. PMID: 24758532
Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects.
Le Coz M, Aktary Z, Watanabe N, Yajima I, Pouteaux M, Charoenchon N, Motohashi T, Kunisada T, Corvelo A, Larue L. Le Coz M, et al. J Invest Dermatol. 2021 May;141(5):1363-1366.e9. doi: 10.1016/j.jid.2020.08.025. Epub 2020 Oct 20. J Invest Dermatol. 2021. PMID: 33091424 Free article. No abstract available.
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.
Cortellino S, Xu J, Sannai M, Moore R, Caretti E, Cigliano A, Le Coz M, Devarajan K, Wessels A, Soprano D, Abramowitz LK, Bartolomei MS, Rambow F, Bassi MR, Bruno T, Fanciulli M, Renner C, Klein-Szanto AJ, Matsumoto Y, Kobi D, Davidson I, Alberti C, Larue L, Bellacosa A. Cortellino S, et al. Among authors: le coz m. Cell. 2011 Jul 8;146(1):67-79. doi: 10.1016/j.cell.2011.06.020. Epub 2011 Jun 30. Cell. 2011. PMID: 21722948 Free PMC article.